Natalie A. Wright

Introduction to Experimental Biology

BIOL 109Y

This is the first laboratory course a student takes and is a prerequisite for all upper-division laboratory courses. Students are introduced to the processes of investigative biology and scientific writing. It is not designed to accompany any particular core lecture course. Laboratories cover topics presented in the core lecture courses, BIOL 115 and 116, and introduce a variety of techniques and topics, including field sampling, microscopy, PCR, gel electrophoresis, enzyme biochemistry, physiology, evolution and population biology. The course emphasizes the development of inquiry skills through active involvement in experimental design, data collection and management, statistical analysis, integration of results with information reported in the literature, and writing in a format appropriate for publication. The year culminates in six-week student-designed investigations that reinforce the research skills developed during the year. Evaluation is based on laboratory notebooks, lab performance, and scientific papers, as well as oral and written presentations summarizing the independent project. Enrollment is limited to 16 students in each section. Students enrolled in this course will be automatically added to BIOL 110Y for the spring semester. Prerequisite: completion or concurrent enrollment in BIOL 115 or equivalent. Required for the major.

Introduction to Experimental Biology

BIOL 110Y

This is the first laboratory course a student takes and is a prerequisite for all upper-division laboratory courses. Students are introduced to the processes of investigative biology and scientific writing. It is not designed to accompany any particular core lecture course. Laboratories cover topics presented in the core lecture courses, BIOL 115 and 116, and introduce a variety of techniques and topics, including field sampling, microscopy, PCR, gel electrophoresis, enzyme biochemistry, physiology, evolution and population biology. The course emphasizes the development of inquiry skills through active involvement in experimental design, data collection, statistical analysis, integration of results with information reported in the literature and writing in a format appropriate for publication. The year culminates in six-week student-designed investigations that reinforce the research skills developed during the year. Evaluation is based on short reports, quizzes, lab performance and scientific papers, as well as oral and written presentations based on the independent project. Enrollment is limited to 16 students in each section. Prerequisite: completion or concurrent enrollment in BIOL 115 or equivalent. Required for the major.

Evolution

BIOL 241

Evolution is the major unifying theory of biology. This course introduces the processes of evolution, most of which can be examined in contemporary time through experiment, theory, simulation and examination of patterns in nature. The class format will combine lecture, activities and discussions. Topics will include Darwinian natural selection, population genetics, adaptation, speciation, reconstructing phylogenetic history, macroevolution, sexual selection, and the consequences of evolution for conservation and human health. Examples will be drawn from all levels of biology, from molecular to ecological. Students will read, analyze and discuss primary literature in the evolutionary biology. This counts toward the upper-level environmental biology requirement for the major. Prerequisite: BIOL 116 or permission of instructor.

Comparative Vertebrate Anatomy

BIOL 247

This course will explore questions of how and why vertebrates came to be structured the way they are. We will use both comparative and functional approaches to study how the anatomy of vertebrates has evolved and diversified over hundreds of millions of years. We will examine how anatomy relates to function; for example, how do different musculoskeletal arrangements allow for different types of movement? We will investigate anatomical adaptations to a variety of environments to understand how different vertebrates have solved anatomical and biomechanical problems. Each of the primary vertebrate organ systems (integument, skeleton, muscle, cardiovascular, respiratory, gastrointestinal, urogenital, nervous) will be covered in detail. Students will read and analyze papers from the primary literature. This counts toward the upper-level organismal biology/physiology requirement for the major. Prerequisite: BIOL 116 and concurrent enrollment in BIOL 248, Vertebrate Anatomy Laboratory. Generally offered every year.

Comparative Vertebrate Anatomy Lab

BIOL 248

This course is a hands-on exploration of the anatomy of vertebrates. Students will learn to identify major components of all of the primary vertebrate organ systems (integument, skeleton, muscle, cardiovascular, respiratory, gastrointestinal, urogenital and nervous). To understand patterns of vertebrate evolution, we will examine and compare specimens from all major vertebrate groups, including mammals, birds, cartilaginous fishes, ray-finned fishes, amphibians and non-avian reptiles, including extinct organisms. We will also perform experiments in biomechanics to understand how vertebrate form shapes function and movement. Dissections are required. Students will be tested via practical quizzes and exams. Prerequisite: BIOL 116 and concurrent enrollment in BIOL 247. Generally offered every year. This counts toward the upper-level laboratory requirement.

ST: Evolution Lab

BIOL 291

Research in Biology

BIOL 385

This combined discussion and laboratory course aims to develop abilities for asking sound research questions, designing reasonable scientific approaches to answer such questions, and performing experiments to test both the design and the question. We consider how to assess difficulties and limitations in experimental strategies due to design, equipment, organism selected and so on. The course provides a detailed understanding of selected modern research equipment. Students select their own research problems in consultation with one or more biology faculty members. This course is designed both for those who plan to undertake honors research in their senior year and for those who are not doing honors but want practical research experience. A student can begin the course in either semester. If a year of credit is earned, it may be applied toward one laboratory requirement for the major in biology. This course is repeatable for credit. Prerequisite: BIOL 109Y–110Y and 116 and permission of instructor.

Individual Study in Biology

BIOL 393

This course provides the student with the opportunity to pursue an independent investigation of a topic of special interest not covered, or not covered in depth, in the current curriculum. The investigation, designed in consultation with the chosen faculty mentor, may be designed to earn .25 or .5 unit of credit in a semester. BIOL 393 is ordinarily is a library-oriented investigation. (For laboratory-oriented independent research, see BIOL 385.) Normally, students receive credit for no more than two semesters of individual study. Individual study does not fulfill the natural science diversification requirement, nor does it count toward the requirements for the major. Because students must enroll for individual studies by the end of the seventh day of classes, they should begin discussion of the proposed individual study well in advance, preferably the semester before, so that there is time to devise a syllabus and seek departmental approval before the established deadline.